Products
N-cadherin antibody
- Product Name
- N-cadherin antibody
- Catalogue No.
- FNab05571
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 1G1
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cadherin 2, type 1, N-cadherin(neuronal)
- Alternative Names
- Cadherin 2 antibody, CD325 antibody, CDH2 antibody, CDHN antibody, CDw325 antibody, N cadherin antibody, NCAD antibody, N-cadherin antibody, Neural cadherin antibody
- UniProt ID
- P19022
- Observed MW
- 130 kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:1000-1:10000; IHC: 1:20-1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab05571(N-cadherin Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab05571(N-cadherin Antibody) at dilution of 1:200
- Background
- Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity).
