Products
MAGEA3 antibody
- Product Name
- MAGEA3 antibody
- Catalogue No.
- FNab04937
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 4E9
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- melanoma antigen family A, 3
- Alternative Names
- Antigen MZ2 D antibody, Cancer/testis antigen 1.3 antibody, CT1.3 antibody, HIP8 antibody, HYPD antibody, MAGE 3 antigen antibody, MAGE3 antibody, MAGEA3 antibody, MAGE-A3 antibody, MAGEA6 antibody, melanoma antigen family A antibody, 3 antibody, Melanoma associated antigen 3 antibody
- UniProt ID
- P43357
- Observed MW
- 35-55 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04937(MAGEA3 Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04937(MAGEA3 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- Background
- Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
