Products
LAS1L antibody
- Product Name
- LAS1L antibody
- Catalogue No.
- FNab04703
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- LAS1-like
- UniProt ID
- Q9Y4W2
- Observed MW
- 83 kDa, 70-75 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04703(LAS1L antibody) at dilution of 1:1000
IP Result of anti-LAS1L (IP:FNab04703, 4ug; Detection:FNab04703 1:1000) with HEK-293 cells lysate 1200ug.
- Background
- Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP(5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
