INTS7 antibody

Synonyms:C1orf73 antibody
Catalogue No.:FNab04364Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
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Product Name
INTS7 antibody
Catalogue No.
FNab04364
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
integrator complex subunit 7
Alternative Names
C1orf73 antibody
UniProt ID
Q9NVH2
Observed MW
107kd
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04364(INTS7 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human brain using FNab04364(INTS7 antibody) at dilution of 1:100
Background
Component of the Integrator complex, a complex involved in the small nuclear RNAs(snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain(CTD) of RNA polymerase II largest subunit(POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response(DDR) signaling during the S phase.