Products
INO80 antibody
- Product Name
- INO80 antibody
- Catalogue No.
- FNab04323
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- INO80 homolog
- Alternative Names
- INO80A antibody, INOC1 antibody, KIAA1259 antibody
- UniProt ID
- Q9ULG1
- Observed MW
- 177,150 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04323(INO80 Antibody) at dilution of 1:600
IP Result of anti-INO80 (IP:FNab04323, 4ug; Detection:FNab04323 1:500) with HeLa cells lysate 2000ug.
- Background
- DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
