Products
IL23A antibody
- Product Name
- IL23A antibody
- Catalogue No.
- FNab04256
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 2G1
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interleukin 23, alpha subunit p19
- Alternative Names
- IL 23 antibody, IL 23 A antibody, IL 23 subunit alpha antibody, IL 23A antibody, IL 23p19 antibody, IL23A antibody, IL23P19 antibody, Interleukin 23 subunit alpha antibody, Interleukin 23 subunit p19 antibody, P19 antibody, SGRF antibody
- UniProt ID
- Q9NPF7
- Observed MW
- 21 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
IL23A transfected HEK293 cells were subjected to SDS-PAGE followed by western blot with FNab04256(IL23A monoclonal Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human pancreas tissue slide using FNab04256(IL23A Antibody) at dilution of 1:50
- Background
- Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
