HSPA1L antibody

Catalogue No.:FNab04055Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, IF, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HSPA1L antibody
Catalogue No.
FNab04055
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
heat shock 70kDa protein 1-like
UniProt ID
P34931
Observed MW
70 kDa
Application
Tested Applications
ELISA, IHC, IF, WB
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab04055(HSPA1L Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab04055(HSPA1L antibody) at dilution of 1:100
Background
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage(By similarity). Positive regulator of PARK2 translocation to damaged mitochondria.