Products
HOOK3 antibody
- Product Name
- HOOK3 antibody
- Catalogue No.
- FNab03968
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- hook homolog 3(Drosophila)
- UniProt ID
- Q86VS8
- Observed MW
- 83 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab03968(HOOK3 antibody) at dilution of 1:500
IP Result of anti-HOOK3 (IP:FNab03968, 4ug; Detection:FNab03968 1:500) with mouse kidney tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human kidney using FNab03968(HOOK3 antibody) at dilution of 1:100
- Background
- Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking(By similarity). Component of the FTS/Hook/FHIP complex(FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex(the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex.
