SW480 cells were subjected to SDS PAGE followed by western blot with FNab03760(HAS3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab03760(HAS3 antibody) at dilution of 1:50
Immunofluorescence analysis of A549 cells using FNab03760(HAS3 antibody) at dilution of 1:100
Background
The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.