Products
GAR1 antibody
- Product Name
- GAR1 antibody
- Catalogue No.
- FNab03346
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- GAR1 ribonucleoprotein homolog(yeast)
- Alternative Names
- NOLA1 antibody
- UniProt ID
- Q9NY12
- Observed MW
- 28kd
Application
- Tested Applications
- ELISA, WB, IHC, IP, IF
- Recommended dilution
- WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
A375 cells were subjected to SDS PAGE followed by western blot with FNab03346(GAR1 antibody) at dilution of 1:500
IP Result of anti-GAR1 (IP: FNab03346, 3ug; Detection: FNab03346 1:500) with A375 cells lysate 3000ug.
Immunohistochemistry of paraffin-embedded human skin cancer using FNab03346(GAR1 antibody) at dilution of 1:50
- Background
- Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein(H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase(TERT) holoenzyme.
