Products
Fibromodulin antibody
- Product Name
- Fibromodulin antibody
- Catalogue No.
- FNab03120
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- fibromodulin
- Alternative Names
- fibromodulin antibody, FM antibody, FMOD antibody, KSPG fibromodulin antibody, SLRR2E antibody
- UniProt ID
- Q06828
- Observed MW
- 45kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse spleen were subjected to SDS PAGE followed by western blot with FNab03120(Fibromodulin Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human hepatocirrhosis tissue slide using FNab03120(Fibromodulin Antibody) at dilution of 1:50
- Background
- Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.
