Products
FBP1 antibody
- Product Name
- FBP1 antibody
- Catalogue No.
- FNab03029
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- fructose-1,6-bisphosphatase 1
- Alternative Names
- FBP antibody, FBP1 antibody, FBPase 1 antibody, fructose 1 antibody, 6 bisphosphatase 1 antibody
- UniProt ID
- P09467
- Observed MW
- 37 kDa
Application
- Tested Applications
- ELISA, IHC, WB, IF, IP
- Recommended dilution
- WB: 1:5000-1:20000; IP: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:50-1:500
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab03029(FBP1 antibody) at dilution of 1:5000
IP Result of anti-FBP1 (IP: FNab03029, 4ug; Detection: FNab03029 1:500) with HepG2 cells lysate 3200ug.
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab03029( FBP1 Antibody) at dilution of 1:200
Immunofluorescent analysis of HeLa cells using FNab03029 (FBP1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
