Jurkat cells were subjected to SDS PAGE followed by western blot with FNab02502(DOK3 antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human lymphoma using FNab02502(DOK3 antibody) at dilution of 1:50
Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function(By similarity).