DGKQ antibody

Synonyms:Diacylglycerol kinase theta (DAG kinase theta antibody, DGKtheta)|Diglyceride kinase theta (DGK-theta)|DGKQ|DAGK4 antibody
Catalogue No.:FNab02361Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
DGKQ antibody
Catalogue No.
FNab02361
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
diacylglycerol kinase, theta 110kDa
Alternative Names
Diacylglycerol kinase theta (DAG kinase theta antibody, DGKtheta)|Diglyceride kinase theta (DGK-theta)|DGKQ|DAGK4 antibody
UniProt ID
P52824
Observed MW
110 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02361(DGKQ antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human cervix using FNab02361(DGKQ antibody) at dilution of 1:50
Background
Phosphorylates diacylglycerol(DAG) to generate phosphatidic acid(PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor(By similarity). May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.