Products
DBF4 antibody
- Product Name
- DBF4 antibody
- Catalogue No.
- FNab02255
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- DBF4 homolog
- Alternative Names
- ASK antibody, DBF4A antibody, ZDBF1 antibody
- UniProt ID
- Q9UBU7
- Observed MW
- 70-80kd
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab02255(DBF4 antibody) at dilution of 1:1000
- Background
- Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
