HeLa cells were subjected to SDS PAGE followed by western blot with FNab02145(CYP17A1 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using FNab02145(CYP17A1 Antibody) at dilution of 1:200
Background
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone(DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.