Products
COX2 antibody
- Product Name
- COX2 antibody
- Catalogue No.
- FNab01897
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- prostaglandin-endoperoxide synthase 2(prostaglandin G/H synthase and cyclooxygenase)
- Alternative Names
- COX 2 antibody, COX2 antibody, Cyclooxygenase 2 antibody, GRIPGHS antibody, hCox 2 antibody, PGG/HS antibody, PGH synthase 2 antibody, PGHS 2 antibody, PHS 2 antibody, PHS II antibody, Prostaglandin G/H synthase 2 antibody, Prostaglandin H2 synthase 2 antibody, PTGS2 antibody
- UniProt ID
- P35354
- Observed MW
- 64 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:10-1:100
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01897(PTGS2 antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab01897(COX2/ Cyclooxygenase 2 Antibody) at dilution of 1:200
Immunofluorescent analysis of HepG2 cells using FNab01897(COX2/ Cyclooxygenase 2 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Background
- Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
