Products
cleaved Caspase 9 antibody
- Product Name
- cleaved Caspase 9 antibody
- Catalogue No.
- FNab01296
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- caspase 9, apoptosis-related cysteine peptidase
- Alternative Names
- APAF 3 antibody, APAF3 antibody, Apoptotic protease Mch 6 antibody, CASP 9 antibody, CASP9 antibody, Caspase 9 antibody, CASPASE 9c antibody, Caspase9 antibody, Caspase-9 antibody, ICE LAP6 antibody, ICE like apoptotic protease 6 antibody, MCH6 antibody
- UniProt ID
- P55211
- Observed MW
- 17kDa/36kDa/46kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:200 - 1:200; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01296 at dilution of 1:300
Immunohistochemistry of paraffin-embedded rat brain using FNab01296 at dilution of 1:100
Immunofluorescence analysis of ( -20℃ Ethanol ) fixed A549 cells using FNab01296.
- Background
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.This antibody can recognize the pre- and cleaved- caspase 9.
