Products
C4 (alpha chain) antibody
- Product Name
- C4 (alpha chain) antibody
- Catalogue No.
- FNab01111
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- complement component 4A(Rodgers blood group)
- UniProt ID
- P0C0L4
- Observed MW
- 95 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:1000-1:6000; IHC: 1:50-1:500
Validated Images
human blood tissue were subjected to SDS PAGE followed by western blot with FNab01111( C4 (alpha chain) antibody at dilution of 1:3000
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab01111( C4 (alpha chain) antibody at dilution of 1:200
- Background
- Complement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular wights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody can recognize C4 precursor, C4 alpha chain, C4b, and C4d.
