C1QC antibody

Synonyms:C1QG antibody
Catalogue No.:FNab01074Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
C1QC antibody
Catalogue No.
FNab01074
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
complement component 1, q subcomponent, C chain
Alternative Names
C1QG antibody
UniProt ID
P02747
Observed MW
26 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human blood tissue were subjected to SDS PAGE followed by western blot with FNab01074(C1QC Antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab01074(C1QC Antibody) at dilution of 1:50
Background
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.