Products
BEX2 antibody
- Product Name
- BEX2 antibody
- Catalogue No.
- FNab00884
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- brain expressed X-linked 2
- Alternative Names
- BEX1 antibody, BEX1/2 antibody, BEX2 antibody, brain expressed X linked 2 antibody, hBex2 antibody, Protein BEX2 antibody
- UniProt ID
- Q9BXY8
- Observed MW
- 10-15 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab00884(BEX2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human breast cancer using FNab00884(BEX2 antibody) at dilution of 1:100
- Background
- Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94%. This antibody detects both BEX1 and BEX2.
