Products
ASTN2 antibody
- Product Name
- ASTN2 antibody
- Catalogue No.
- FNab00652
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- astrotactin 2
- Alternative Names
- ASTN2 antibody, astrotactin 2 antibody, KIAA0634 antibody
- UniProt ID
- O75129
- Observed MW
- 148 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00652(ASTN2 Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab00652(ASTN2 Antibody) at dilution of 1:50
- Background
- Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1(By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup(Ref.6).
