Products
ARRDC3 antibody
- Product Name
- ARRDC3 antibody
- Catalogue No.
- FNab00608
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- arrestin domain containing 3
- Alternative Names
- ARRDC3 antibody, arrestin domain containing 3 antibody, KIAA1376 antibody, TLIMP antibody
- UniProt ID
- Q96B67
- Observed MW
- 46 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:1000; IF: 1:10-1:100
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab00608( ARRDC3 Antibody) at dilution of 1:600
- Background
- Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors(PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation(PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2(PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes(PubMed:23208550).
