mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab00572(ARL13B Antibody) at dilution of 1:1000
IP Result of anti-ARL13B (IP: FNab00572, 3ug; Detection: FNab00572 1:1000) with L02 cells lysate 2500ug.
Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab00572(ARL13B Antibody) at dilution of 1:200
Background
Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidences are required to confirm these data.