Products
ACPP antibody
- Product Name
- ACPP antibody
- Catalogue No.
- FNab00102
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 8D6
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- acid phosphatase, prostate
- Alternative Names
- Acid phosphatase antibody, prostate antibody, ACP 3 antibody, ACP3 antibody, ACPP antibody, PAP antibody, Prostatic acid phosphatase antibody
- UniProt ID
- P15309
- Observed MW
- 48 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
human testis tissue were subjected to SDS PAGE followed by western blot with FNab00102(ACPP antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human prostate hyperplasia using FNab00102(ACPP antibody) at dilution of 1:50
- Background
- A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions(pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion(DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
