ACE(Angiotensin Converting Enzyme 1) Eukaryotic Protein

ACE (peptidyl-dipeptidase A) is a kind of zinc metallopeptidase, which plays an important role in blood-pressure control and water-salt metabolism. The widely expressed ACE shows the highest content in lung, kidney, heart, gastrointestinal system and prostate.
ACE has two main functions: 1. catalyze and convert angiotensin I into angiotensin II; 2. inactivate bradykinin. Thus, it's the suitable target for the treatment of hypertension, heart failure, diabetes mellitus type 2, diabetes and kidney diseases.
Currently, FineTest has developed the active ACE protein expressed by eukaryotic expression system and uses it in the related Elisa kit.

Catalogue No.: P8059
Synonyms: ACE, ACE1, Angiotensin converting enzyme, CD143, DCP, DCP1, Dipeptidyl carboxypeptidase I, Kininase II, MVCD3
Species: Human
Uniprot ID: P12821
Expression Region: 30-1232
Source: HEK 293 cells
Tags: C-terminal His Tag
Molecular Weight: 140 kDa
Purity: Greater than 95% by SDS-PAGE gel analyses
Activity: Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK(Dnp)-OH (R&D Systems, Catalog # ES005).
The specific activity is >1,000 pmol/min/µg, as measured under the described
Formulation: Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.06% proclin, pH7.4
Reconstitution: Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 200 μg/ml in sterile distilled water
Storage: -20°C for 12 months as lyophilized; 2-8°C for 1 month under sterile conditions after reconstitution
Image: ACE-wb
Human ACE(Angiotensin I Converting Enzyme) ELISA Kit (EH0026)
Recombinant Human ACE2 (P2955)