FineTest
Mainly focused on Lab research Products, Manufacturer of ELISA kits, Antibodies, Proteins
-
English (US) -
简体中文
Mainly focused on Lab research Products, Manufacturer of ELISA kits, Antibodies, Proteins
English (US) 简体中文 
| Product Information | |
|---|---|
| Product name | anti- PARP1 antibody |
| Catalogue No. | FNab09939 |
| Size | 100µg |
| Form | liquid |
| Purification | protein A+G purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Mouse |
| Isotype | IgG1 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
| Background | |
PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis. | |
| Immunogen Information | |
| Immunogen | poly (ADP-ribose) polymerase 1 |
| Synonyms | ADPRT, ADPRT 1, ADPRT1, pADPRT 1, PARP, PARP 1, PARP1, poly (ADP ribose) polymerase 1, Poly [ADP ribose] polymerase 1, Poly[ADP ribose] synthase 1, PPOL |
| Calculated MW | 115 kDa, 89 kDa |
| Application | |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IHC, IF |
| Recommended dilution | WB: 1:5000 – 1:30000; IHC: 1:100 – 1:1000; IF: 1:50 – 1:500 |
| Uniprot information | |
| Uniprot ID | |
| Images | |
 anti- PARP1 antibody 1 Immunohistochemistry of paraffin-embedded human breast cancer using FNab09939(PARP1 antibody) at dilution of 1:600 | |
 anti- PARP1 antibody 1 HeLa cells were subjected to SDS PAGE followed by western blot with FNab09939(PARP1 Antibody) at dilution of 1:20000 | |
Current product's manual: Manual
Protocol may be updated. Please feel free to contact Finetest Team to acquire the latest version.