FOXO4 antibody

Synonyms:Forkhead box protein O4|Fork head domain transcription factor AFX1|FOXO4|AFX|AFX1|MLLT7 antibody
Catalogue No.:FNab03204Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
FOXO4 antibody
Catalogue No.
FNab03204
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
forkhead box O4
Alternative Names
Forkhead box protein O4|Fork head domain transcription factor AFX1|FOXO4|AFX|AFX1|MLLT7 antibody
UniProt ID
P98177
Observed MW
45-48 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab03204(FOXO4 antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human kidney using FNab03204(FOXO4 antibody) at dilution of 1:100
Background
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements(IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells(ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.