Monkeypox virus is a self-limiting zoonotic disease caused by DNA virus. It has the typical form of orthopoxvirus, with rounded brick or oval shape and size of 200-400m. Components: brick-shaped or oval-shaped, covered by a protein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core. The core contains a large double-stranded DNA gene body, and its genome is double-stranded DNA, about 197 kb in length, containing an identical but opposite inverted terminal repeat at the end of the genome. The virus contains 190 open reading frames, 4 of which are located in inverted terminal repeats. The main symptoms after infection usually include fever, severe headache, muscle aches, back pain, lack of energy, swollen lymph nodes, and rash or skin lesions. About 3-6% of cases currently reported in endemic countries result in death.