High IF Citations

【Cited FineTest Elisa Kit】 Current Research on Nanomaterials for Vascular Tissue Engineering

FineTest Elisa kit contributes to the research on nanomaterials for vascular tissue engineering. The immunoassay is designed to measure P-Selectin concentration in plasma.

Publication Details
Article Title: In Vivo Performance of Electrospun Tubular Hyaluronic Acid/Collagen Nanofibrous Scaffolds for Vascular Reconstruction in the Rabbit Model
Journal Title: Journal of Nanobiotechnology
DOI: 10.1186/s12951-021-01091-0
IF: 10.435
PMID: 34717634

Abstract:    One of the main challenges of tissue-engineered vascular prostheses is restenosis due to intimal hyperplasia. The aim of this study is to develop a material for scaffolds able to support cell growth while tolerating physiological conditions and maintaining the patency of carotid artery model. Tubular hyaluronic acid (HA)-functionalized collagen nanofibrous composite scaffolds were prepared by sequential electrospinning method. The tubular composite scaffold has well-controlled biophysical and biochemical signals, providing a good matrix for the adhesion and proliferation of vascular endothelial cells (ECs), but resisting to platelets adhesion when exposed to blood. Carotid artery replacement experiment from 6-week rabbits showed that the HA/collagen nanofibrous composite scaffold grafts with endothelialization on the luminal surface could maintain vascular patency. At retrieval, the composite scaffold maintained good structural integrity and had comparable mechanical strength as the native artery. This study indicating that electrospun scaffolds combined with cells may become an alternative to prosthetic grafts for vascular reconstruction.
Keywords:   Blood Vessel, Collagen, Hyaluronic Acid, Patency, Scaffold

Immunoassay

FineTest Product Sample Detection Target Species
Rabbit SELP(P-Selectin) ELISA Kit (ERB0112) plasma P-Selectin Rabbit