Products
MLF1 antibody
- Product Name
- MLF1 antibody
- Catalogue No.
- FNab05210
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- myeloid leukemia factor 1
- Alternative Names
- Myeloid leukemia factor 1|Myelodysplasia-myeloid leukemia factor 1|MLF1 antibody
- UniProt ID
- P58340
- Observed MW
- 31 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab05210(MLF1 antibody) at dilution of 1:500
IP Result of anti-MLF1 (IP:FNab05210, 4ug; Detection:FNab05210 1:500) with mouse heart tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human colon cancer using FNab05210(MLF1 antibody) at dilution of 1:100
- Background
- Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
