mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab07195(RBPJ antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab07195(RBPJ antibody) at dilution of 1:100
Background
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.