BCL2 antibody

Synonyms:Apoptosis regulator Bcl 2 antibody, B cell CLL/lymphoma 2 antibody, BCL2 antibody, Oncogene B cell leukemia 2 antibody
Catalogue No.:FNab00839Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
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Product Name
BCL2 antibody
Catalogue No.
FNab00839
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
B-cell CLL/lymphoma 2
Alternative Names
Apoptosis regulator Bcl 2 antibody, B cell CLL/lymphoma 2 antibody, BCL2 antibody, Oncogene B cell leukemia 2 antibody
UniProt ID
P10415
Observed MW
26 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200
Validated Images
HL-60 cells were subjected to SDS PAGE followed by western blot with FNab00839( Bcl2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab00839( BCL2 Antibody) at dilution of 1:200.
Immunofluorescent analysis of NIH/3T3 cells, using BCL2 antibody FNab00839 at 1:100 dilution and FITC-labeled goat anti-rabbit IgG (green).
Background
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.