CLDN3 antibody

Synonyms:Claudin-3|Clostridium perfringens enterotoxin receptor 2 (CPE-R 2 antibody, CPE-receptor 2)|Rat ventral prostate.1 protein homolog (hRVP1)|CLDN3|C7orf1|CPETR2 antibody
Catalogue No.:FNab01738Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CLDN3 antibody
Catalogue No.
FNab01738
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
claudin 3
Alternative Names
Claudin-3|Clostridium perfringens enterotoxin receptor 2 (CPE-R 2 antibody, CPE-receptor 2)|Rat ventral prostate.1 protein homolog (hRVP1)|CLDN3|C7orf1|CPETR2 antibody
UniProt ID
O15551
Observed MW
21 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Validated Images
mouse colon tissue were subjected to SDS PAGE followed by western blot with FNab01738( Claudin 3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab01738( Claudin 3 Antibody) at dilution of 1:100
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.