Products
CRCP antibody
- Product Name
- CRCP antibody
- Catalogue No.
- FNab01955
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CGRP receptor component
- Alternative Names
- DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9)|Calcitonin gene-related peptide-receptor component protein (CGRP-RCP antibody, CGRP-receptor component protein antibody, CGRPRCP antibody, HsC17)|CRCP antibody
- UniProt ID
- O75575
- Observed MW
- 20 kDa
Application
- Tested Applications
- ELISA, WB, IHC, FC, IP
- Recommended dilution
- WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
Raji cells were subjected to SDS PAGE followed by western blot with FNab01955(CRCP antibody) at dilution of 1:1000
IP Result of anti-CRCP (IP: FNab01955, 4ug; Detection: FNab01955 1:1000) with Raji cells lysate 3000ug.
Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab01955(CRCP Antibody) at dilution of 1:50
- Background
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
