Products
anti- IL-6 antibody
- Product Name
- anti- IL-6 antibody
- Catalogue No.
- FNab04283
- Size
- 100µg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 6D11
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interleukin 6(interferon, beta 2)
- Alternative Names
- B cell stimulatory factor 2 antibody, BSF 2 antibody, BSF2 antibody, CDF antibody, CTL differentiation factor antibody, HGF antibody, HSF antibody, Hybridoma growth factor antibody, IFN beta 2 antibody, IFNB2 antibody, IL 6 antibody, IL6 antibody, IL-6 antibody, Interferon beta 2 antibody, Interleukin 6 antibody
- UniProt ID
- P05231
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200
验证图片
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04283(IL6 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using FNab04283(IL6 Antibody) at dilution of 1:50
- Background
- Interleukin-6(IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.