Products

anti- IL-6 antibody

FNab04283 Catalogue No.
Synonyms
B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HGF, HSF, Hybridoma growth factor, IFN beta 2, IFNB2, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6
Host
Mouse
Reactivity
Human
Isotype
IgG2a
Tested Application
ELISA, IHC, WB
Product Information
Product Name
anti- IL-6 antibody
Catalogue No.
FNab04283
Size
100µg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Host
Mouse
Clonality
monoclonal
Isotype
IgG2a
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
Immunogen Information
Immunogen
interleukin 6 (interferon, beta 2)
Synonyms
B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HGF, HSF, Hybridoma growth factor, IFN beta 2, IFNB2, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6
Application
Tested Application
ELISA, IHC, WB
Recommended dilution
WB: 1:500-1:5000;IHC: 1:20-1:200
Uniprot information
UniProt ID
P05231
Images
Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using FNab04283 (IL6 Antibody) at dilution of 1:50
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04283 (IL6 antibody) at dilution of 1:1000