HepG2 cells were subjected to SDS PAGE followed by western blot with FNab10488(MAS1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse kidney tissue slide using FNab10488(MAS1 antibody) at dilution of 1:50
Background
This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7).