Products
NCOA6 antibody
- Product Name
- NCOA6 antibody
- Catalogue No.
- FNab05591
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nuclear receptor coactivator 6
- Alternative Names
- AIB3 antibody, KIAA0181 antibody, RAP250 antibody, TRBP antibody
- UniProt ID
- Q14686
- Observed MW
- 68 kDa ; 219 kDa ; 110 kDa
Application
- Tested Applications
- ELISA, IP
- Recommended dilution
- IP: 1:200-1:2000
Validated Images
IP Result of anti-NCOA6 (IP:FNab05591, 4ug; Detection:FNab05591 1:1000) with HEK-293 cells lysate 2560ug.
- Background
- Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist-and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids(GR and ERs), retinoids(RARs and RXRs), thyroid hormone(TRs), vitamin D3(VDR) and prostanoids(PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.
