HeLa cells were subjected to SDS PAGE followed by western blot with FNab05003(MARCH5 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab05003(MARCH5 Antibody) at dilution of 1:50
Background
Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1.