HeLa cells were subjected to SDS PAGE followed by western blot with FNab03012(FANCM antibody) at dilution of 1:300
Background
ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.