Creatine Kinase MM-Specific antibody

Synonyms:CKMM antibody, Creatine Kinase MM antibody, Creatine Kinase M-Specific antibody, Creatine kinase M chain antibody, Creatine kinase M type antibody, creatine kinase antibody, muscle antibody, M CK antibody
Catalogue No.:FNab01957Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Creatine Kinase MM-Specific antibody
Catalogue No.
FNab01957
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
creatine kinase, muscle
Alternative Names
CKMM antibody, Creatine Kinase MM antibody, Creatine Kinase M-Specific antibody, Creatine kinase M chain antibody, Creatine kinase M type antibody, creatine kinase antibody, muscle antibody, M CK antibody
UniProt ID
P06732
Observed MW
43 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:1000-1:10000; IHC: 1:20-1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab01957(CKM-Specific antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human skeletal muscle using FNab01957(CKM-Specific antibody) at dilution of 1:100
Background
CKM, also named as CKMM and M-CK, is a member of the ATP:guanido phosphotransferase protein family. It is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. CKM reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissus,and as a heterodimer with a similar brain isozyme in heart. CK isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. CK MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, esp