AADACL1 antibody

Category: Research Area:
Synonyms:AADACL1 antibody, KIAA1363 antibody, KIAA1363 antibody, NCEH1 antibody, NCEH antibody, NCEH antibody, NCEH1 antibody
Catalogue No.:FNab00017Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP,IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
AADACL1 antibody
Catalogue No.
FNab00017
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
arylacetamide deacetylase-like 1
Alternative Names
AADACL1 antibody, KIAA1363 antibody, KIAA1363 antibody, NCEH1 antibody, NCEH antibody, NCEH antibody, NCEH1 antibody
UniProt ID
Q6PIU2
Observed MW
50-55 kDa
Application
Tested Applications
ELISA, WB, IHC, IP,IF
Recommended dilution
WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab00017(AADACL1 antibody) at dilution of 1:500
IP Result of anti-AADACL1 (IP:FNab00017, 4ug; Detection:FNab00017 1:500) with COLO 320 cells lysate 400ug.
Immunohistochemistry of paraffin-embedded human brain using FNab00017(AADACL1 antibody) at dilution of 1:50
Background
AADACL1(Arylacetamide deacetylase-like 1) is also named as NCEH1, KIAA1363 and belongs to the 'GDXG' lipolytic enzyme family. The transmembrane enzyme, AADACL1, controls the production of the monoalkylglycerol ether(MAGE) class of NELs in cancer cells and acts as a 2-acetyl MAGE hydrolase and is likely the principal source for this activity in tumor cells(PMID:21513884). The full length protein has three glycosylation sites and can be N-glycosylated(PMID:19159218). It has 3 isoforms produced by alternative splicing.