Products
ZAK antibody
- Product Name
- ZAK antibody
- Catalogue No.
- FNab09581
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- sterile alpha motif and leucine zipper containing kinase AZK
- Alternative Names
- AZK antibody, HCCS 4 antibody, MLK related kinase antibody, MLK7 antibody, mlklak antibody, MLT antibody, MLTK antibody, MRK antibody, ZAK antibody
- UniProt ID
- Q9NYL2
- Observed MW
- 55 kDa, 100 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09581(ZAK antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon carcinoma slide using FNab09581( ZAK Antibody) at dilution of 1:50
- Background
- This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
