Products
VAMP7/TI-VAMP antibody
- Product Name
- VAMP7/TI-VAMP antibody
- Catalogue No.
- FNab09364
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- vesicle-associated membrane protein 7
- Alternative Names
- SYBL1 antibody, Synaptobrevin like protein 1 antibody, Tetanus insensitive VAMP antibody, TI VAMP antibody, TI-VAMP antibody, VAMP 7 antibody, VAMP7 antibody
- UniProt ID
- P51809
- Observed MW
- 20 kDa, 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200；IF: 1:10-1:100; IP: 1:500-1:5000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09364(VAMP7 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human small intestine using FNab09364(VAMP7 antibody) at dilution of 1:50
- Background
- VAMP7, also named as SYBL1 and TI-VAMP, belongs to the synaptobrevin family. It is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. VAMP7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. It is required for calcium regulated lysosomal exocytosis. VAMP7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. It is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. It is also required for focal exocytosis of late endocytic vesicles during phagosome formation. The antibody is specific to VAMP7.
