Products
UGDH antibody
- Product Name
- UGDH antibody
- Catalogue No.
- FNab09238
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- UDP-glucose dehydrogenase
- Alternative Names
- GDH antibody, UDP Glc dehydrogenase antibody, UDP GlcDH antibody, UDP glucose 6 dehydrogenase antibody, UDP glucose dehydrogenase antibody, UDPGDH antibody, UGD antibody, UGDH antibody
- UniProt ID
- O60701
- Observed MW
- 60 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09238(UGDH antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab09238(UGDH antibody) at dilution of 1:100
Immunofluorescence analysis of HeLa cells using FNab09238(UGDH antibody). Blue: DAPI for nuclear staining.
- Background
- The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.
