Products
TXNDC5 antibody
- Product Name
- TXNDC5 antibody
- Catalogue No.
- FNab09127
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- thioredoxin domain containing 5 (endoplasmic reticulum)
- Alternative Names
- EndoPDI antibody, ER protein 46 antibody, ERP46 antibody, Hcc 2 antibody, PDIA15 antibody, Thioredoxin like protein p46 antibody, TLP46 antibody, TXNDC5 antibody, UNQ364 antibody
- UniProt ID
- Q8NBS9
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09127(TXNDC5 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab09127(TXNDC5 antibody) at dilution of 1:100
- Background
- This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
