Products
TSG-6 antibody
- Product Name
- TSG-6 antibody
- Catalogue No.
- FNab09041
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tumor necrosis factor, alpha-induced protein 6
- Alternative Names
- Hyaluronate binding protein antibody, TNF alpha induced protein 6 antibody, TNF stimulated gene 6 protein antibody, TNFAIP6 antibody, TSG 6 antibody, TSG6 antibody
- UniProt ID
- P98066
- Observed MW
- 41 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab09041( TNFAIP6 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab09041( TNFAIP6 Antibody) at dilution of 1:100
- Background
- The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
