mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with FNab08175(SPHK2 antibody) at dilution of 1:300
IP Result of anti-SPHK2 (IP:17096-1-AP, 4ug; Detection:17096-1-AP 1:800) with mouse liver tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab08175(SPHK2 Antibody) at dilution of 1:200
Background
Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate(SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.