Products
SKAP2 antibody
- Product Name
- SKAP2 antibody
- Catalogue No.
- FNab07890
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- src kinase associated phosphoprotein 2
- Alternative Names
- PRAP antibody, RA70 antibody, SAPS antibody, SCAP2 antibody, SKAP55R antibody
- UniProt ID
- O75563
- Observed MW
- 50 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab07890(SKAP2 antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded mouse stomach using FNab07890( SKAP2 Antibody) at dilution of 1:50
- Background
- The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.
