Products
SETDB1 antibody
- Product Name
- SETDB1 antibody
- Catalogue No.
- FNab07771
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SET domain, bifurcated 1
- Alternative Names
- KIAA0067 antibody, KMT1E antibody
- UniProt ID
- Q15047
- Observed MW
- 210 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab07771(SETDB1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab07771(SETDB1 antibody) at dilution of 1:100
- Background
- This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
